Prednisolone Rhinosinusitis Efficacy Trial (PRET) study

Phase 3

Completed

• Conditions: rhinosinusitis; sinusitis; 10047438

• Registration Number: NL-OMON33569
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

Patients with rhinosinusitis-like symptoms - according to the criteria of the guidelines of the Dutch College of General Practitioners - for at least 5 days;Age > 18 years

Exclusion Criteria

Fever > 38.5°C (measured by GP);> 2 episodes of RS in the previous 12 months;use of either nasal or oral corticosteroids in the previous 4 weeks;Contraindication for prednisolone treatment;Pregnancy;Previous ENT surgery for malignant disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Resolution of facial pain at day 7.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Resumption of daily activities (school/work), health related quality of life<br /><br>and cost-effectiveness.</p><br>