Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients

Not Applicable

Not yet recruiting

• Conditions: ACL Reconstruction; ACL Surgery; ACL Injury; Electrotherapy; Muscle Atrophy or Weakness

• Registration Number: NCT07171346
• Lead Sponsor: University of Kansas Medical Center

Brief Summary

This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.

Detailed Description

The addition of neuromuscular electrical stimulation (NMES) to standard ACLR rehabilitation has been demonstrated to improve knee extension and flexion compared to standard treatment only. NMES has also shown improved lower limb loading symmetry, walking velocity, stance time, cadence, maximum voluntary isometric contraction, motor unit behavior, muscle quality, and an increase in absolute muscle strength in functional tests compared to standard care of ACLR recovery. In this study we will be comparing bi-lateral presurgical and post surgical muscle strength symmetry in patients that follow the standard ACLR rehabilitation program and patients that use the NMES in addition to standard rehab.

Study Timeline

• Study First Submitted: 2025-08-22
• Status Verified: 2025-09
• Study First Submitted QC: 2025-09-05
• Last Update Submitted: 2025-09-05
• Study First Posted: 2025-09-12
• Last Update Posted: 2025-09-12
• Study Start: 2025-11-01
• Primary Completion: 2027-11
• Study Completion: 2028-06-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• ACLR surgical patients at KUMC sports medicine
• 15 to 50 years old
• BMI between 18 - 30 kg/m2
• No limitations impacting physical function within the last 6 months (not including the ACL injury)

Exclusion Criteria

• Previous lower limb or spine injury involving surgical treatment
• Prior spine surgery
• Lower limb injury (other than ACL) preventing participation in physical activity for over two weeks in the past 6 months
• Non english speaking
• Vulnerable population, prisoner, or ward of the state

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Bilateral Muscle Symmetry Index	pre-operative to 3 months post-op	Comparing muscle size strength and function between operative and non-operative limbs

Trial Locations

Locations (1)

University of Kansas Medical Center; 🇺🇸 Kansas City, Kansas, United States