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Clinical Trials/NCT04254159
NCT04254159
Completed
N/A

The Effects of Neuromuscular Electrical Stimulation to Muscle Strength, Functional Capacity and Quality of Life in Older Patients With Asthma: Randomized Controlled Trial

Yeditepe University1 site in 1 country24 target enrollmentDecember 5, 2019
ConditionsAsthma

Overview

Phase
N/A
Intervention
Not specified
Conditions
Asthma
Sponsor
Yeditepe University
Enrollment
24
Locations
1
Primary Endpoint
Sit to Stand Test
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The aim of the randomized controlled study is to investigate the effects of NMES superimposed on voluntary contraction combined with patient education and exercise training program in patients with chronic obstructive pulmonary disease.

Detailed Description

When initial assessments will be completed, patients will be assigned to one of two possible sequences by simple randomization: Superimposed NMES group (SG) or control group (CG). All volunteers will receive an COPD patient education program for once and conventional physiotherapy exercise program for COPD with the duration of 8 weeks. Additionally, superimposed NMES will be applied on quadriceps muscle of both limbs at the same time with voluntarily contraction of quadriceps muscle in SG. All patients will be assessed in terms of functional capacity, pulmonary functions, quadriceps muscle endurance and strength, dyspnea, respiratory muscle strength and quality of life at the baseline and at the end of study. Data will be collected from all the patients at baseline and at the end of study (8 weeks) by the same physiotherapist who also will supervise the exercise sessions.

Registry
clinicaltrials.gov
Start Date
December 5, 2019
End Date
May 22, 2020
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Elif Develi

Physiotherapist

Yeditepe University

Eligibility Criteria

Inclusion Criteria

  • Having stable asthma
  • Participating to the study in a voluntary basis
  • Being 65 - 75 years old
  • Having 2 point or over score from "Modified Medical Research Council (MMRC)" Dyspnea Scale
  • Being motivated to participate and follow exercise program

Exclusion Criteria

  • Having an asthma exacerbation in a last month
  • Other respiratory problems
  • Ischemic heart disease
  • Congestive heart disease
  • Acute Cor Pulmonale
  • Neurological Diseases
  • Osteoporosis

Outcomes

Primary Outcomes

Sit to Stand Test

Time Frame: 8 weeks

Quadriceps muscle endurance will be evaluated with this test

Muscle Strength Test

Time Frame: 8 weeks

Jtech Commander Power Track Muscle Testing Dynamometer, USA which quantifies muscle power will be used to assess the maximum voluntary contractions of quadriceps muscle in pound meter.

Six Minute Walking Test

Time Frame: 8 weeks

Six-Minute Walking Test (6MWT) was used to evaluate functional capacity of volunteers.

Asthma Quality of Life Scale (AQOL)

Time Frame: 8 weeks

Asthma quality of life questionnaire will utilize to assess quality of life of participants over two weeks prior to interview which is validated in Turkish population by Alpaydın et al.

Secondary Outcomes

  • Time Up and Go Test(8 weeks)
  • Modified Medical Research Council (MMRC) Dyspnea Scale(8 weeks)
  • Respiratory Muscle Strength Testing(8 weeks)
  • Pulmonary Function Test(8 weeks)
  • Physical Activity Questionnaire for Elderly (PASE)(8 weeks)

Study Sites (1)

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