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Clinical Trials/NCT06947785
NCT06947785Not yet recruitingNot Applicable

Effectiveness of Combined Neural Mobilization With Manual Myofascial Release for Sciatic Pain Relief

Riphah International University1 site in 1 country48 target enrollmentStarted: April 15, 2025Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
48
Locations
1
Primary Endpoint
Numerical pain rating scale

Study Overview

Brief Summary

This study will address to evaluate and compare both Neural mobilization and Manual Myofascial Release of piriformis and Lumbar muscles in sciatic pain with the aim of evaluating and identifying the most effective intervention for managing this specific condition, and provide valuable insights into the effectiveness, mechanisms, and practical considerations associated with these interventions, ultimately contributing to evidence based and patient centered care.

Detailed Description

MFR is a hands-on technique targeting fascial restrictions that may contribute to pain and reduced mobility. Barnes proposed that releasing fascial adhesions can improve circulation, reduce nerve compression, and enhance tissue flexibility. In a study by Ajimsha et al. , MFR was found to significantly reduce pain and improve physical function in patients with nonspecific low back pain. There is a lack of comparative research assessing the relative efficacy of neural mobilization andMFR in sciatic pain management. While both techniques are rooted in distinct mechanisms neural desensitization versus fascial release they may have overlapping benefits in improving mobility and reducing pain. This study addresses this research gap by directly comparing the two approaches in individuals with sciatic pain.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
20 Years to 40 Years (Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Clinically diagnosed unilateral sciatic pain for >3 months.
  • •Positive Straight Leg Raise (SLR).

Exclusion Criteria

  • •Participants fall in this category would be excluded of the study.
  • •Recent spinal surgery or trauma.
  • •Neurological deficits or systemic conditions affecting the nervous system.
  • •Any other red flags

Arms & Interventions

Combined Neural Mobilization with Manual myofascial Release

Experimental

Combined neural mobilization of Sciatic nerve and manual myofascial release of piriformis and back muscles will be given to this group.

Intervention: Combined Neural Mobilization with Manual myofascial Release (Other)

Neural Mobilization

Active Comparator

Only neural mobilization of Sciatic nerve will be given to this group.

Intervention: Neural Mobilization (Other)

Manual Myofascial Release

Active Comparator

Only manual myofascial release of piriformis and back muscles will be given to this group.

Intervention: Manual Myofascial Release (Other)

Outcomes

Primary Outcomes

Numerical pain rating scale

Time Frame: Four Weeks

A subjective pain assessment tool where patients rate their pain intensity on a scale from 0 (no pain) to 10 (worst imaginable pain).

Universal Goniometer

Time Frame: Four Weeks

Joint range of motion will be measured using a Universal Goniometer in degrees (°). Each joint movement will be assessed individually. The goniometer will be used following standardized procedures as per the American Academy of Orthopaedic Surgeons (AAOS) guidelines. Unit of Measure is degrees.

Patient-Specific Functional Scale

Time Frame: Four Weeks

The Patient-Specific Functional Scale is a validated patient-reported outcome measure used to assess functional limitations based on activities identified by the patient. Participants will rate their ability to perform 3-5 self-selected activities that are important to them, using an 11-point scale ranging from 0 to 10. Minimum score: 0 (indicating the patient is unable to perform the activity) Maximum score: 10 (indicating the patient can perform the activity at their prior level with no difficulty) Interpretation: Higher scores indicate better functional status. The average score across all selected activities will be used for analysis.

SLR (Straight Leg Raise)

Time Frame: Four Weeks

A clinical test used to assess sciatic nerve irritation or lumbar radiculopathy by raising the extended leg while the patient lies supine.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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