Investigation of the progression of atherosclerosis and atherosclerotic risk factor in patients with diabetes
Not Applicable
- Conditions
- Diabetes
- Registration Number
- JPRN-UMIN000014765
- Lead Sponsor
- Division of diabetes, Mitsui Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 700
Inclusion Criteria
Not provided
Exclusion Criteria
1.post PCI and CABG 2.post implantation of peacemaker and ICD or CRT 3.cardiac shock 4.severe heart failure (more than NYHA3) 5.Cre more than1.5mg/dl 6.pheochromocytoma 7.bronchial asthma 8.Allergy of contrast agent 9.Severe thyroid disease 10.previous severe allergy to something 11.Pregnant, lactating, possibly pregnant or planning to become pregnant women 12.Malignant tumor 13.Patients considered as inadequate by the principal investigator
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) All cause death, 2)Cardiovascular events (composite of cardiovascular death, non-fatal myocardial infarction, unstable angina pectoris, non-fatal ischemic stroke, hospitalization for heart failure, coronary revascularization, or hospitalization for peripheral artery disease) 3)new onset cardiovascular disease 4)new onset LV dysfunction 5)plaque volume (coronary and carotid) 6)BMI
- Secondary Outcome Measures
Name Time Method 1)Change in endothelial function 2)New onset of cardic valvular disease 3)New onset of arrythmia 4) Change in fasting glucose, HbA1c, body weight, insulin resistance and secretion, BNP, Hs-CRP, lipids, PUFAs, UACA, CTR, ABI, cartid echography, and ECG.