TCTR20230616002
Completed
Phase 4
Primary (Immediate) Reconstruction Using Nonvascularized Bone Grafts For Large Defects in Mandibular Chronic Suppurative Osteomyelitis
Mosaad Khalifah0 sites21 target enrollmentJune 16, 2023
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Osteomyelitis of the mandible
- Sponsor
- Mosaad Khalifah
- Enrollment
- 21
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1 Patients diagnosed with chronic suppurative osteomyelitis of the mandible based on the clinical picture (pain, tenderness, fever, lymphadenitis, painful or painless swelling, intraoral and or skin fistula(e), purulent discharge, hypoesthesia of the inferior dental nerve (IAN), and trismus), radiographic examination (moth\-eaten appearance), and the histopathologic examination (necrotic bone, granulation tissue, inflammatory cells, and blood vessel thrombosis).
- •2 The proposed resection size be 6 cm or more; however, with the presence of sufficient mandibular bone at the inferior border of the mandible following the proposed marginal resection.
Exclusion Criteria
- •1 The more extensive involvement of the mandible necessitating segmental resection
- •2 History of recent head or neck radiotherapy, concurrent head or neck radiotherapy, co\-presence of malignancies, kidney\-, liver\-, or heart failure, any other bone marrow diseases, and immune diseases.
Outcomes
Primary Outcomes
Not specified
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