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Ondansetron for the Treatment of Methamphetamine Dependence - 1

Phase 2
Completed
Conditions
Amphetamine-Related Disorders
Registration Number
NCT00040053
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Brief Summary

The purpose of this study is to assess ondansetron for the treatment of methamphetamine dependence.

Detailed Description

This study was designed to be a preliminary assessment of the efficacy and safety of 3-wide range doses of ondansetron (0.25, 1.0 and 4.0 mg taken orally twice per day) to reduce methamphetamine use in subjects with methamphetamine dependence and to determine the optimal dose of ondansetron.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
154
Inclusion Criteria

18 years of age. Treatment seeking for meth dependence.

Exclusion Criteria

Please contact site director for more details.

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Clinicial improvement
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (6)

South Bay Treatment Center

🇺🇸

Chula Vista, California, United States

John A. Burns School of Medicine

🇺🇸

Honolulu, Hawaii, United States

Powell Chemical Dependency Center

🇺🇸

Des Moines, Iowa, United States

Matrix Institute on Addictions

🇺🇸

Costa Mesa, California, United States

University of Missouri - Kansas City

🇺🇸

Kansas City, Missouri, United States

University of Texas Health Science Center

🇺🇸

Houston, Texas, United States

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