Study of Naltrexone for Methamphetamine Addiction

Phase 2

Completed

• Conditions: Methamphetamine Dependence
• Interventions: Drug: Naltrexone

• Registration Number: NCT00984360
• Lead Sponsor: California Pacific Medical Center Research Institute

Brief Summary

The purpose of this study is to determine whether methamphetamine-dependent individuals will use less methamphetamine when treated with naltrexone. The study will also investigate whether individuals with the mu opioid receptor gene variant A118G will use less methamphetamine than individuals without A118G.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09
• Study First Submitted: 2009-09-14
• Study First Submitted QC: 2009-09-24
• Study First Posted: 2009-09-25
• Primary Completion: 2011-07
• Study Completion: 2012-09
• Status Verified: 2013-05
• Last Update Submitted: 2013-05-29
• Last Update Posted: 2013-05-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

• Age between 18 and 50 years
• Patient is agreeable to conditions of study and signs consent form

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
A118G	Naltrexone	-
Wild-type	Naltrexone	-

Primary Outcome Measures

Name	Time	Method
MA (-) Urine Samples	Twice weekly for 5 weeks

Trial Locations

Locations (1)

Addiction & Pharmacology Research Laboratory; 🇺🇸 San Francisco, California, United States