MedPath

Prospective Collection of PillCam SB3 Videos and Raw Data Files for Future Developments (SODA)

Active, not recruiting
Conditions
Small Intestine Adenocarcinoma
Small Intestine Polyp
Small Intestine Cancer
Small Intestine Obstruction
Small Intestinal Ulcer Bleeding
Small Intestine Disease
Registration Number
NCT03771508
Lead Sponsor
Medtronic - MITG
Brief Summary

Observational, Multicenter, Post-market, Minimal risk, Prospective data collection of PillCam SB3 videos (including PillCam reports) and raw data files and optional collection of Eneteroscopy reports

Detailed Description

Up to 8000 PillCam SB3 videos (including PillCam reports) and raw data files will be collected in up to 50 medical centers in the US. Study duration is up to 7 years from IRB approval.

Medical center study sites will provide relevant videos (including PillCam reports) and raw data from patients who underwent SB3 procedures.

Per patient demographic data will be also collected to provide a description of the study population characteristics and disposition.

Additional Standard of care data collection might be performed (optional). This data will include a de-identified Eneteroscopy report, from patients enrolled to the study and referred to Eneteroscopy procedure (all types of Eneteroscopies), following findings identified during the PillCamTM SB procedure, as part of the standard of care procedure. This data might be collected retrospectively for enrolled patients who underwent an Eneteroscopy procedure. The de-identified reports will be used by MDT GI research and development team to further develop and validated SB capsule localization.

Study subjects will not undergo any additional procedures, nor will their diagnosis and subsequent treatment pathway be changed for the purpose of the registry.

The data will be used by MDT GIs research and development team for the development and validation of improved and new detectors in the PillCam software.

The videos (including PillCam reports) and raw data files will be de-identified at the medical center by representatives who are authorized and delegated to review medical records, prior to providing them to the sponsor. All data in the study- videos, reports, raw data files and demographic information will be de-identified in a manner that is untraceable by the sponsor clinical study team members.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
8000
Inclusion Criteria
  • All SB3 cases collected during standard of care procedures.
  • The subject received an explanation and understands the nature of the study and provided oral consenting
Exclusion Criteria
  • None

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Prospective collection of PillCam SB3 videosUp to 7 years from study approval

sponsor database will be expanded with images of pathologies and normal mucosa for future development and validation of improved algorithms for GI pathologies detection with the PillCam platform

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (30)

Rhode Island Hospital

🇺🇸

Providence, Rhode Island, United States

Palmetto Primary Care

🇺🇸

Summerville, South Carolina, United States

Austin Gastro

🇺🇸

Austin, Texas, United States

Birmingham Gastroenterology Associates

🇺🇸

Birmingham, Alabama, United States

Gastroenterology & Liver Institute

🇺🇸

Escondido, California, United States

Amicis Research Center

🇺🇸

Valencia, California, United States

Medical Research Center of Connecticut

🇺🇸

Hamden, Connecticut, United States

Encore Borland-Groover

🇺🇸

Jacksonville, Florida, United States

Research Associates of South Florida

🇺🇸

Miami, Florida, United States

University of Miami Miller School of Medicine

🇺🇸

Miami, Florida, United States

Digestive Healthcare of GA

🇺🇸

Atlanta, Georgia, United States

The University of Kansas Medical Center

🇺🇸

Kansas City, Kansas, United States

Capital Digestive Care

🇺🇸

Chevy Chase, Maryland, United States

Gastro Center of Maryland

🇺🇸

Columbia, Maryland, United States

Woodholme Gastroenterology Associates

🇺🇸

Pikesville, Maryland, United States

UMass Memorial Health Care

🇺🇸

Worcester, Massachusetts, United States

Digestive Health Associates

🇺🇸

Farmington Hills, Michigan, United States

Clinical Research Professionals

🇺🇸

Chesterfield, Missouri, United States

The Children's Mercy Hospital

🇺🇸

Kansas City, Missouri, United States

Atlantic Digestive Health Institute

🇺🇸

Morristown, New Jersey, United States

Albany Gastroenterology Consultants

🇺🇸

Albany, New York, United States

Erber M.D. PC

🇺🇸

Brooklyn, New York, United States

Northwell Health - Cohen Children's Medical Center of New York

🇺🇸

Lake Success, New York, United States

New York Gastroenterology Associates

🇺🇸

New York, New York, United States

University Hospitals Cleveland Medical Center

🇺🇸

Cleveland, Ohio, United States

The Ohio State University Wexner Medical Center

🇺🇸

Columbus, Ohio, United States

The Toledo Clinic

🇺🇸

Toledo, Ohio, United States

Digestive Disease Specialists Inc

🇺🇸

Oklahoma City, Oklahoma, United States

USDH Clinical Research

🇺🇸

Exton, Pennsylvania, United States

Thomas Jefferson University

🇺🇸

Philadelphia, Pennsylvania, United States

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