Effectivity and Working Mechanisms of Schema Therapy for patients with a Treatment Resistant Depressio

Phase 2

Recruiting

• Conditions: Chronic Depression; Treatment Resistant Depression; 10027946

• Registration Number: NL-OMON50591
• Lead Sponsor: ProPersona (Nijmegen)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

• Adult defined as 16 years or older;
• Primary diagnosis is treatment resistant or recurrent depression according to
DSM-5 criteria evident from the MINI 5.0;
• IDS-SR score of 26 or higher, indicating average, severe or very severe
depressive symptoms;
• Evident from the intake interview report: a pattern of noticeable behaviour
or internal experience which can be typed as traits of a personality disorder;
• Evident from the intake interview report: a previously used evidence based
psychological treatment (e.g. CBT, IPT, CBASP) or pharmacological treatment for
treatment resistant depression or for the current depression in case of
recurring depression;

Exclusion Criteria

• Primary diagnosis is personality disorder;
• Current psychotic disorder;
• Lifetime bipolar disorder, substance use disorder or autism spectrum disorder;
• Insufficient mastery of the Dutch language;
• Impossibility to give a valid informed consent;
• Cognitive or intellectual impairments (IQ below 80) interfering with
participation judged by the therapist;
• Changes in treatment policy caused by suicidal ideations or medication
changes;
• Contraindication to group therapy at the end of the case conceptualization.
The two most obvious indications are presence of Angry Child-Bully and
Attack-Enraged Child coping mode.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Depressive symptoms as measured by the QIDS-SR.</p><br>