A human pilot study to investigate the effect of daily consumption of gold kiwifruit for 2 weeks on transcriptomic changes in buccal epithelial cells and blood in healthy males.
- Conditions
- InflammationOral HealthInflammatory and Immune System - Normal development and function of the immune systemOral and Gastrointestinal - Normal oral and gastrointestinal development and function
- Registration Number
- ACTRN12620001359921
- Lead Sponsor
- Plant & Food Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Male
- Target Recruitment
- 6
Healthy individuals (male) 18-60 years, who are not following any specialised diets and can complete the dietary requirements of the trial will be selected (determined in familiarisation session).
Participants will be required to complete a health questionnaire and provide written consent for this study.
Participants will be excluded if they are unwilling or unable to provide informed written consent or comply with study procedures.
All participants will be in good cardiovascular and oral health and did not report any use of antibacterial mouthwash or antibiotics for at least 6 months prior to study commencement. They were free from non-prescription medication including those known to interfere with stomach acid production. Participants will also be excluded if they have (i) known hypersensitivity or intolerance to kiwifruit, In addition, participants will be excluded if they have any of the following conditions: blood borne diseases (e.g., hepatitis), (ii) clinically diagnosed high/low blood pressure, (iii) recent bacterial or viral illness, (iv) are taking any medication that affects the properties of blood (e.g. blood clotting) (iv) oral health conditions (e.g., recent dental work, tooth decay & periodontal diseases).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method