Comparative Evaluation Of Efficacy Of Intraligamentary Injection Using Articaine, Ketorolac And Dexamethasone For Reduction Of Endodontic Pain In Symptomatic Irreversible Pulpitis: A Randomized Double Blinded Clinical Study

A total of 81 patients experiencing endodontic pain and requiring root canal treatment were enrolled after informed consent. Following baseline VAS assessment, all patients received a standard Inferior Alveolar Nerve Block using 2 percent Lignocaine with Adrenaline. Those who experienced pain during access cavity initiation were included. Participants were randomised via sealed envelopes into three groups to receive an intraligamentary injection of either articaine, dexamethasone, or ketorolac. The double-blind technique was employed, and injections were administered with back-pressure at the mesiobuccal and distobuccal line angles. Post-injection VAS scores were recorded upon pulpal chamber access. In cases of persistent pain, intrapulpal lignocaine was used. Standardised endodontic procedures followed, including rubber dam isolation, working length determination, rotary instrumentation, irrigation with EDTA and sodium hypochlorite, and obturation with gutta-percha and zinc oxide eugenol sealer using cold lateral compaction. Composite restoration completed the procedure.