Differentiating simple from complex appendicitis in children before surgery: The Complex Appendicitis Tool (CAT)
- Conditions
- Complex appendicitisSimple appendicitis100179661000401810017998
- Registration Number
- NL-OMON43987
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
3.1 Population (base)
All children 0-17 presenting at the ER department in one of the three hospitals with the suspicion of an acute appendicitis are eligible for inclusion.;3.2 Inclusion criteria (in the simple or complex appendicitis group)
All children 0-17 presenting at the ER department in one of the three hospitals with the suspicion of an acute appendicitis are eligible for inclusion.;3.3 Control group
Children presenting at the ER with abdominal pain with the suspicion of acute appendicitis, although non-infectional cause or no cause was found however.
Age older than 17 years old
Appendicular infiltrate
Appendectomy a froid
Appendix Sana
Malignancy of the appendix
Non-operative management
Abdominal pain caused by other infectious disease such as lymphadenitis mesenteric, pneumonia etcetera.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Type of appendicitis, gender, age, symptoms at time of presentation, duration<br /><br>of abdominal pain, fever, heart rate, laboratory results at the time of<br /><br>diagnosis, findings on radiological imaging. Per operative findings and<br /><br>conclusion.<br /><br><br /><br>Immunology: levels of cytokines, kind of leucocytes in peripheral blood samples.<br /><br><br /><br>Histopathology: number and kind of immune cells in the appendix. Cellular<br /><br>staining by flowcytometry<br /><br><br /><br>Bacteriology: Microbiome</p><br>
- Secondary Outcome Measures
Name Time Method <p>nvt</p><br>