The effect of erector spinae block on inflammatory mediators and stress hormone in traumatic spine surgeries Randomised prospective control trial
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Effect of Erector spinae block on inflammatory mediators IL-1beta, IL-6 and TNF-alpha and serum cortisol levels
研究概览
简要总结
In this study we aim to determine the effect of erector spinae block on inflammatory mediators and stress hormone in traumatic spine surgeries;to study and compare peri-operative hemodynamic parameters; to assess post-operative pain;to note complications, if any. We aim to establish the effect of erector spinae block on inflammatory markers
( IL-1β, IL-6, TNF-α) and serum cortisol levels post operatively in traumatic spinal injury patients undergoing surgery
and its further impact on peri-operative hemodynamic parameters, post operative pain and safety outcome and
patient satisfaction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Includes those undergoing traumatic Thoracolumbar spine surgeries belonging to American society of anaesthesiologists physical status 1 and 2.
排除标准
- •Patient refusal Age more than 60 or less than 18 Patient with uncontrolled hypertension diabetes mellitus immunological disorders Patients having allergy to any of the drugs administered Obesity with BMI more than 30 kg per metre squared.
结局指标
主要结局
Effect of Erector spinae block on inflammatory mediators IL-1beta, IL-6 and TNF-alpha and serum cortisol levels
时间窗: Parameters to be checked immediately post extubation, after 24 hours, 48 hours post surgery
次要结局
- Effect of Erector spinae block on perioperative hemodynamics & post operative pain-VAS score(Perioperative hemodynamics -baseline, After 15 minutes 30 minutes, 45 minutes, 60 minutes, 75 minutes)
研究者
Sumita Kumari
Banaras Hindu University