The TRAC-SI (Triage of Acute Chest pain using Speckle tracking Imaging) trial
- Conditions
- Acute coronary syndrome
- Registration Number
- JPRN-UMIN000013859
- Lead Sponsor
- Department of Cardiology, Kansai Electric Power Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 403
Not provided
Patients who meet any one of the following conditions are excluded from the trial. 1)Patients who show signs of moderate congestive heart failure (NYHA III or higher) 2)Patients who are in shock 3)Patients with LVEF less than 50% 4)Patients with left bundle branch block 5)Patients with a history of myocardial infarction or other myocardial disease 6)Patients with valvular heart disease for which invasive treatment is judged to be necessary 7)Patients in whom acceptable ultrasound images cannot be obtained 8)Patients who are found to have abnormal cardiac wall contraction by echocardiography 9)Patients with atrial fibrillation 10)Patients with a heart rate of 40 bpm or less or 100 bpm or higher 11)Patients with a serum creatinine level of 2.0 or higher 12)Patients with a history of allergy to contrast medium 13)Patients who are pregnant or breastfeeding, patients who may be pregnant 14)Patients who should be excluded from the trial for medical reasons, based on the judgment of their attending physician
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method sing the final diagnosis of ACS (truth standard) as the true value (sick or healthy), sensitivity is assessed for each of the three protocols: (1) combination of initial diagnosis and 2D speckle tracking echocardiography (Index + 2DST method), (2) initial diagnosis alone (Index method), and (3) 2D speckle tracking echocardiography alone (2DST method).
- Secondary Outcome Measures
Name Time Method specificity, positive predictive value, and negative predictive value of above.