Changes in vascular function after a reduced sitting interventio

Completed

• Conditions: prolonged sitting; sedentary behaviour; 10024450

• Registration Number: NL-OMON45705
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-03-01
• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

- * 45 (male) or *55 (women) years of age
- At least one of the following CV risk factors:
o High blood pressure (i.e. Systolic blood pressure >160 mmHg or diastolic blood pressure >90mmHg
o BMI>28kg/m2
- Mentally able/allowed to give informed consent
- Seated behaviour > 40 hours per week

Exclusion Criteria

- Persons who are not physically able to perform light-intensity physical activity such as standing and walking.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) Periferal vascular function </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>2) Cerebral autoregulation<br /><br>3) Blood markers of metabolic status, NO-pathway and inflammation.</p><br>