The effect of ketamine and midazolam combination in comparison to ketamine and morphine for pain treatment
Phase 3
Recruiting
- Conditions
- acute pain in emergency department.Acute pain, not elsewhere classified
- Registration Number
- IRCT20171106037280N2
- Lead Sponsor
- kurdistan university of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 168
Inclusion Criteria
moderate to severe pain
acute pain at emergency department
age 18-55
Exclusion Criteria
allergy to drugs
pregnancy or lactation
elevated intracerebral or intraocular pressure
chronic pain
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain intensity. Timepoint: 15,30,60,90, and 120 min after drug adminidtrstion. Method of measurement: numeric rating scale (NRS).
- Secondary Outcome Measures
Name Time Method Changes in blood pressure. Timepoint: 15,30,60,90, and 120 min after drug administration. Method of measurement: measurement of blood pressure by the sphygmomanometer.;Nausea and vomiting. Timepoint: from beginning to the end (120 min after drug administration). Method of measurement: observation.;Dizziness. Timepoint: from beginning to the end (120 min after drug administration). Method of measurement: history taking and asking from the patient.;Behavioral change. Timepoint: from drug administration to 120 min afterwards. Method of measurement: observation.;Delusion and hallucinations. Timepoint: from drug administration to 120 min afterwards. Method of measurement: observation and history taking.;Changes in O2 saturation. Timepoint: from drug administration to 120 min afterwards. Method of measurement: continuous pulse oximetry.