Comparison of the effect of midazolam-ketamine with ketamine-propofol on post-tonsillectomy agitation in childre

Phase 2

• Conditions: Tonsillectomy.; Chronic tonsillitis; J35.01

• Registration Number: IRCT20141009019470N92
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

ASA I-II
Airway class I-II
Normal BMI
children aged 5-15
children candidate for elective adenotonsillectomy
Isoflurane based anesthesia

Exclusion Criteria

History of neuropsychiatric illness
CHD
URTI
Seizure
Drug reactions
Any history of post operation complications
Any complication of surgery or anesthesia that could cause agitation itself

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sedation. Timepoint: At arrival to recovery room 5 minute, 10 minute, 20 minute and on recovery room discharge. Method of measurement: Richmond Agitation & Sedation Scale (RASS).;Pain. Timepoint: At arrival to recovery room 5 minute, 10 minute, 20 minute and on recovery room discharge. Method of measurement: Objective Pain Scale (OPS).;Recover duration. Timepoint: At arrival to recovery room 5 minute, 10 minute, 20 minute and on recovery room discharge. Method of measurement: Modified Aldrete score.