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临床试验/NCT05809570
NCT05809570已完成不适用

Periodontal Disease Prediction System and a Patient-Specific Gingival Recession Simulator

Bezmialem Vakif University1 个研究点 分布在 1 个国家目标入组 1,057 人开始时间: 2020年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,057
试验地点
1
主要终点
Number of sites Clinical Attachment Loss≥5 mm

研究概览

简要总结

The purpose of this study was to develop a periodontal disease prediction software and a patient-based gingival recession simulator for clinical practice aiming at improving oral hygiene motivation of patients with periodontal problems.

详细描述

Periodontal Disease Prediction (PDP) software has three components: a) Data Loading Window (DLW) b) Three-Dimensional Mouth Model (3DM) and c) Periodontal Attachment Loss Indicator (PLI). Demographic and clinical examinations of 1057 volunteers were recorded to DLW. An unsupervised machine learning K means clustering analysis was used to categorize the data obtained from the study population and identified the periodontal risk groups. An intraoral scanner was utilized to capture direct optical intraoral data of a patient and transferred to the 3DM. The intraoral model went under two algorithm steps for obtaining a recessed model. First, gingival curves separating gingiva and tooth were extracted using a Dijkstra's algorithm. Limit curves determining boundaries of recessed regions in the intraoral model were then obtained using gingival curves. The gingival recession was then mimicked by losing gingiva and disappearing tooth roots at proper locations in the intraoral model and Additionally, the final four different 3 dimensional recessed model (maxilla, mandibula, anterior teeth and posterior teeth) belonging to the same patient were scored based on the similarity to the real gingival recession by 25 periodontology specialist via online survey.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age greater than 18 years,
  • Periodontal status ranging from no clinical periodontal disease (<10% with bleeding on probing) to periodontitis (stage I to IV)
  • Patients having at least one teeth in each quadrant were included.

排除标准

  • Patients undergoing orthodontic treatment and using anti-inflammatory drugs were excluded.

结局指标

主要结局

Number of sites Clinical Attachment Loss≥5 mm

时间窗: Baseline

Categorized as: None, \<4, 4-8, \>8

次要结局

  • Patient cooperation and awareness(Baseline)
  • Presence of endodontic tooth problem(Baseline)
  • Interproximal cleaning(Baseline)
  • Alveolar bone loss/age(Baseline)
  • Tooth mobility(Baseline)
  • Presence of diabetes(Baseline)
  • Gingival phenotype(Baseline)
  • Vertical alveolar bone loss(Baseline)
  • Restorations including gingival margin(Baseline)
  • History of dental treatment(Baseline)
  • Tooth brushing Habits(Baseline)
  • Number of sites Probing Pocket Depth ≥5 mm(Baseline)
  • Number of sites Bleeding on Probing (%)(Baseline)
  • Traumatic occlusion(Baseline)
  • Smoking status(Baseline)
  • Presence of furcation involvement(Baseline)
  • Number of tooth loss(Baseline)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Şadiye GÜNPINAR

Principal Investigator

Bezmialem Vakif University

研究点 (1)

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