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Periodontal Disease Prediction System

Completed
Conditions
Periodontal Diseases
Interventions
Diagnostic Test: Clinical examination
Registration Number
NCT05809570
Lead Sponsor
Bezmialem Vakif University
Brief Summary

The purpose of this study was to develop a periodontal disease prediction software and a patient-based gingival recession simulator for clinical practice aiming at improving oral hygiene motivation of patients with periodontal problems.

Detailed Description

Periodontal Disease Prediction (PDP) software has three components: a) Data Loading Window (DLW) b) Three-Dimensional Mouth Model (3DM) and c) Periodontal Attachment Loss Indicator (PLI). Demographic and clinical examinations of 1057 volunteers were recorded to DLW. An unsupervised machine learning K means clustering analysis was used to categorize the data obtained from the study population and identified the periodontal risk groups. An intraoral scanner was utilized to capture direct optical intraoral data of a patient and transferred to the 3DM. The intraoral model went under two algorithm steps for obtaining a recessed model. First, gingival curves separating gingiva and tooth were extracted using a Dijkstra's algorithm. Limit curves determining boundaries of recessed regions in the intraoral model were then obtained using gingival curves. The gingival recession was then mimicked by losing gingiva and disappearing tooth roots at proper locations in the intraoral model and Additionally, the final four different 3 dimensional recessed model (maxilla, mandibula, anterior teeth and posterior teeth) belonging to the same patient were scored based on the similarity to the real gingival recession by 25 periodontology specialist via online survey.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1057
Inclusion Criteria
  • Age greater than 18 years,
  • Periodontal status ranging from no clinical periodontal disease (<10% with bleeding on probing) to periodontitis (stage I to IV)
  • Patients having at least one teeth in each quadrant were included.
Exclusion Criteria
  • Patients undergoing orthodontic treatment and using anti-inflammatory drugs were excluded.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Periodontal examinationClinical examinationCross- sectional clinical periodontal examinations and measurements were performed using a Williams periodontal probe
Primary Outcome Measures
NameTimeMethod
Number of sites Clinical Attachment Loss≥5 mmBaseline

Categorized as: None, \<4, 4-8, \>8

Secondary Outcome Measures
NameTimeMethod
Presence of endodontic tooth problemBaseline

Categorized as: Presence/absence

Patient cooperation and awarenessBaseline

Categorized as: None, some, high

Interproximal cleaningBaseline

Categorized as: None/ 1 time in day/ ≥2 times in day

Alveolar bone loss/ageBaseline

Categorized as: None/ \<0.25 /0.25-1/ \>1

Tooth mobilityBaseline

Categorized as: None/ Miller I/ Miller II/ Miller III

Presence of diabetesBaseline

Categorized as: Absence, diabetes with HbA1c\<7, diabetes with HbA1c≥7

Gingival phenotypeBaseline

Categorized as: Thin/thick

Vertical alveolar bone lossBaseline

Categorized as: Presence/absence

Restorations including gingival marginBaseline

Categorized as: Presence/absence

History of dental treatmentBaseline

Categorized as: None, treated in the last 1 year

Tooth brushing HabitsBaseline

Categorized as: None/ 1 time in day/ ≥2 times in day

Number of sites Probing Pocket Depth ≥5 mmBaseline

Categorized as: None/ \<4 / 4-8/ \>8

Number of sites Bleeding on Probing (%)Baseline

Categorized as: \<10%/ 10-25%/ \>25%

Traumatic occlusionBaseline

Categorized as: Presence/absence

Smoking statusBaseline

Categorized as: None, \< 10 per day, ≥10 per day

Presence of furcation involvementBaseline

Categorized as: None/ horizontal involvement/ vertical involvement/ combined

Number of tooth lossBaseline

Categorized as: None/ \<4/ 4-8/ \>8

Trial Locations

Locations (1)

Bezmialem Vakif University

🇹🇷

Istanbul, Turkey

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