anti-pruritic effrcts of curcumin on refractory burn itching
- Conditions
- Burn pruritus.Other pruritusL29.8
- Registration Number
- IRCT20170609034406N7
- Lead Sponsor
- Ardabil University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 100
Age over 18 years ; Having itching after burn injury ; Ability to understand and sign consent form
Other causes of pruritus including renal failure ; Pregnancy; presence of any chronic active, uncontrolled or severe inflammatory disease ( such as autoimmune diseases, connective tissue disease, malignancy, HIV, liver disease and pulmonary disease) ;Breastfeeding ; involvement in other clinical trials ; malabsorption syndrome ; Bleeding disorders ( Including coagulopathies) or high risk for bleeding ;intake of a curcumin supplement or other supplements that affecting itching such as omega_3 in the recent month ; Intolerance or allergy to curcumin ; Receiving drugs that have an effect on inflammatory factors ( sach as corticosteroids or other immunosuppressive drugs, non-steroidal anti-inflammatory drugs, pentoxifylline) in the recent 6 weeks; Use of warfarin ; Abuse of alcohol and other substances that cause dependence.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pruritus score. Timepoint: Before starting the intervention, Six weeks after the intervention and at the end of the intervention period. Method of measurement: Standard questionnaire.
- Secondary Outcome Measures
Name Time Method Quality of life. Timepoint: Before starting the intervention, Six weeks after the intervention and at the end of the intervention. Method of measurement: Standard questionnaire.