Evaluation of Pediatric Measles Cases in 2019: Single-Center Experience
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Evaluate the effect of measles vaccination status on symptom duration
研究概览
简要总结
Measles, can be prevented and eliminated by vaccination, is a highly contagious viral disease that can lead to serious complications, disability, and death. As a result of the World Health Organization (WHO) and United Nations International Children's Emergency Fund (UNICEF) strategic plans, the annual global incidence of measles decreased by 75% over the period 2000-2015, and the estimated global mortality rate fell by 73%. For the current 2019 period, the European and the Eastern Mediterranean Region has recorded respectively more than two-fold and 1.5-fold increase in reported measles cases. As it is known, no specific antiviral treatment exists for the measles virus therefore, vaccination is still the most effective method of preventing disease.
The aim of this study was to evaluate the measles cases in districts where the refugees live quite intensely.
详细描述
Measles, can be prevented and eliminated by vaccination, is a highly contagious viral disease that can lead to serious complications, disability, and death. As a result of the World Health Organization (WHO) and United Nations International Children's Emergency Fund (UNICEF) strategic plans, the annual global incidence of measles decreased by 75% over the period 2000-2015, and the estimated global mortality rate fell by 73%. For the current 2019 period, the European and the Eastern Mediterranean Region has recorded respectively more than two-fold and 1.5-fold increase in reported measles cases. As it is known, no specific antiviral treatment exists for the measles virus therefore, vaccination is still the most effective method of preventing disease.
The aim of this study was to evaluate the measles cases in districts where the refugees live quite intensely.
This retrospective study was consecutively enrolled children who were considered as suspicious measles case according to with clinical features and attended in Esenler Gynecology and Pediatrics Hospital Pediatric Clinic between 01 January-30 June 2019.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 1 Month 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The suspicious case of measles
- •Measles/Rubella Case Notification and Laboratory request and result form and Measles/ Rubella Case Study form must be filled
- •Accept the informed consent form
- •Positive Measles Ig M and Measles Ig G laboratory test
排除标准
- •Rejected the informed consent form
结局指标
主要结局
Evaluate the effect of measles vaccination status on symptom duration
时间窗: baseline
compare the groups symptom durations (day) who fully, partly or not vaccinated
Evaluate the effect of vitamin A treatment on symptom duration
时间窗: in the first month after the first symptom observed
compare the groups symptom durations (day) who get or not get vitamin A treatment
次要结局
- Evaluate the effect of measles vaccination status on leucocyte count(baseline)
- Evaluate the effect of vitamin A treatment on leucocyte count(baseline)