Submaximal exercise testing to assess the anaerobic threshold in neuromuscular diseases
- Conditions
- Slowly progressive neuromuscular diseases
- Registration Number
- NL-OMON27717
- Lead Sponsor
- Amsterdam UMC
- Brief Summary
ot applicable
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 50
In order to be eligible to participate in this study, a subject must meet all of the following criteria:
-presence of slowly progressive NMD.
-ability to perform a maximal exercise test on an arm or bicycle ergometer.
-minimum age of 18 years.
A potential subject who meets any of the following criteria will be excluded from participation in this study:
-absolute contraindication for exercise (based on the guidelines by the American College of Sports Medicine)
-unable to follow verbal or written instructions.
-insufficient mastery of the Dutch or English language.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Validity of statistical model to determine the anaerobic threshold out of easy to measure indirect variables (heart rate variability, rating of perceived exertion, Talk Test, age, gender, resting heart rate)
- Secondary Outcome Measures
Name Time Method - The percentage of times that the AT can be determined through submaximal exercise testing with respiratory gas analysis<br><br>- The test-retest reliability of the heart rate at the anaerobic threshold determined through submaximal exercise testing with respiratory gas analysis