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Submaximal exercise testing to assess the anaerobic threshold in neuromuscular diseases

Recruiting
Conditions
Slowly progressive neuromuscular diseases
Registration Number
NL-OMON27717
Lead Sponsor
Amsterdam UMC
Brief Summary

ot applicable

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
50
Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all of the following criteria:

-presence of slowly progressive NMD.
-ability to perform a maximal exercise test on an arm or bicycle ergometer.
-minimum age of 18 years.

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:

-absolute contraindication for exercise (based on the guidelines by the American College of Sports Medicine)
-unable to follow verbal or written instructions.
-insufficient mastery of the Dutch or English language.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Validity of statistical model to determine the anaerobic threshold out of easy to measure indirect variables (heart rate variability, rating of perceived exertion, Talk Test, age, gender, resting heart rate)
Secondary Outcome Measures
NameTimeMethod
- The percentage of times that the AT can be determined through submaximal exercise testing with respiratory gas analysis<br><br>- The test-retest reliability of the heart rate at the anaerobic threshold determined through submaximal exercise testing with respiratory gas analysis
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