the Efficacy of Transversus Abdominis Plane Block for Analgesia in Comparison With Local Anesthetic Wound Infiltration Post-cesarean Section: A Randomized Comparative Double-blinded Clinical Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obstetric Pain
- Sponsor
- Cairo University
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- degree of pain at rest and on movement (hip flexion and coughing) at 2, 4, 6, 12, and 24 hours postoperatively
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives for reducing the severity of pain, total analgesic consumption, and opioid side effects. Both the TAP block and wound infiltration are superior to placebo; however, it is unknown which provides better analgesia after cesarean delivery because of a scarcity of randomized clinical trials. So, we hypothesized that the TAP block would decrease postoperative pain and postoperative cumulative opioid consumption at 24 hours
Investigators
ahmed nagy shaker ramadan
assistant lecture of obstetrics and gynecology
Cairo University
Eligibility Criteria
Inclusion Criteria
- •Women who underwent cesarean section under spinal anesthesia.
- •Aged ≥19 years and less than 40 years.
- •Gestational age ≥ 37 Weeks.
Exclusion Criteria
- •Body mass index (BMI) ≥40 kg/m
- •History of recent opioid exposure
- •Hypersensitivity to any of the drugs used in the study.
- •Significant cardiovascular, renal, or hepatic disease
Outcomes
Primary Outcomes
degree of pain at rest and on movement (hip flexion and coughing) at 2, 4, 6, 12, and 24 hours postoperatively
Time Frame: 24 hours
, using a visual analog scale (VAS) score for pain intensity reported on 0-10-point scale for analysis. (0 = no pain and 10 = the worst possible pain).
Secondary Outcomes
- measures the time to the first postoperative opioid dose(24 hours)