Effect of Eccentric Strengthening Exercise in Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- Not Applicable
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Pain (Numeric Pain Rating Scale), Pressure Pain Threshold (Algometer), Muscle strength (Sphygmomanometer), Functional disability (WOMAC)
研究概览
简要总结
We plan to carry out a six weeks randomized clinical trial. We will compare the effectiveness between eccentric and isometric strengthening exercise for participants with knee osteoarthritis. This study aims to determine the knee osteoarthritis-related sociodemographic characteristics, baseline comparison at pretest and determine the effectiveness of eccentric strengthening exercise on pain, pressure pain threshold, muscle strength, functional disability, range of motion, six minutes walk test and depression severity of knee osteoarthritis patients after completing interventions. There will be also a follow-up period for 12 weeks. We expect better treatment outcome after 18 sessions of intervention for knee osteoarthritis participants who receive eccentric strengthening exercise along with conventional care.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 45.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Individuals will be included in this trial if (1) ages 45 – 70 for both men and women, (2) the presence of unilateral knee OA for at least six months following American College of Rheumatology criteria, (3) able to walk without the use of any aids and able to flex the knee beyond 90 degrees, (4) anterior-posterior bilateral standing radiograph presents Kellgren and Lawrence Grade II/III knee OA, and (5) absence any unusual cardiac response during the six-minute walk test.
排除标准
- •Individuals will be excluded if (1) knee surgery has been performed in the previous twelve months, (2) lumbar radiculopathy, vascular claudication, severe anterior-sided knee pain resulting from patella-femoral syndrome or chondromalacia, as well as further neurological, muscular, or joint conditions that could impair the function of the lower limbs, (3) visible malformation of the knee, either varus or valgus, (4) Received hyaluronic acid or corticosteroid injections within three months of study enrollment, (5) pregnancy, and (6) BMI over 30.
结局指标
主要结局
Pain (Numeric Pain Rating Scale), Pressure Pain Threshold (Algometer), Muscle strength (Sphygmomanometer), Functional disability (WOMAC)
时间窗: 5 months
次要结局
- Range of Motion (Goniometer), Aerobic Capacity (6MWT), Depression severity (PHQ-9)(5 months)
研究者
Kazi Md Azman Hossain
Jashore University of Science and Technology (JUST), Jashore