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New Serum Biomarkers for Monitoring Early Diagnosis of Ovarian Cancer Recurrence

Recruiting
Conditions
Ovarian Cancer
Registration Number
NCT05410028
Lead Sponsor
Peking Union Medical College Hospital
Brief Summary

In this study, mass spectrometry was used to analyze immune inflammation-related protein complexes, post-translational modified glycopeptide omics and tumor-related metabolomics in serum, respectively, in order to find potential metabolic small molecule biomarkers or marker profiles that can be used for early diagnosis of cancer recurrence.

Detailed Description

Time cohort study: patients with confirmed ovarian epithelial cancer at different time cutoff points before treatment, after surgery, during chemotherapy, and after chemotherapy, until clinically confirmed patients relapse. At least 50 patients are expected to be enrolled.

Recruitment & Eligibility

Status
RECRUITING
Sex
Female
Target Recruitment
1000
Inclusion Criteria
  • Female
  • A diagnosed patient with epithelial ovarian cancer
  • Age ≤ 70
Exclusion Criteria
  • Male
  • Suffering from other malignant tumors
  • Non-compliant patient
  • Age above 70

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Immune Inflammation-Related Protein Complexes2 years

The change of immune inflammation-related protein complexes

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Peking Union Medical College Hospital

🇨🇳

Beijing, Beijing, China

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