Effects of Exercise and Virtual Reality on Depression

Not Applicable

Recruiting

• Conditions: Symptoms of Depression
• Interventions: Other: Riding a cycle ergometer; Device: Exercise and virtual reality

• Registration Number: NCT05973461
• Lead Sponsor: The University of Texas at Arlington

Brief Summary

This study is evaluating the effects of riding on a cycle ergometer while experiencing virtual reality to determine its effect on mood.

Detailed Description

Adults (males and females) above the age of 18 yrs will be recruited to determine if they have symptoms of depression based on a questionnaire (Center for Epidemiologic Studies - Depression Scale (CES-D). They will then complete a Beck Inventory before and after the exercise. Participants will be divided into groups either having symptoms of depression or not. They will be randomized to ride on a cycle ergometer with or without using Virtual Reality (VR) that will allow them to view neighborhoods or parks during the exercise. The ergometer will be set at resistance raising the heart rate to 65% of their age-predicted heart rate maximum. They will ride for 20 min and then complete the Beck Inventory to determine any changes in their depressive symptoms.

Study Timeline

• Study Start: 2022-05-17
• Study First Submitted: 2023-05-11
• Study First Submitted QC: 2023-07-31
• Study First Posted: 2023-08-02
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-08
• Last Update Posted: 2024-04-09
• Primary Completion: 2025-06-14
• Study Completion: 2025-06-14

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Males and females over the age of 18 years
• With or without symptoms of depression
• Physically inactive or sedentary (less than 30 minutes per day)
• Normal vision and no color blindness
• No physical disorders such as walking with assistance

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Exclusion Criteria

• Below the age of 18 years or over 65 years,
• Women who are pregnant
• Individuals who have been diagnosed with mental disorders
• Individuals with leg injuries
• Individuals with cardiac problems
• Individuals with a history of asthma
• Individuals with a body mass index over 30.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Cycle Ergometer	Riding a cycle ergometer	30 min ride on cycle ergometer
Cycle Ergometer and Virtual Reality	Exercise and virtual reality	30 min ride on cycle ergometer while viewing neighborhood scenes using virtual reality

Primary Outcome Measures

Name	Time	Method
Spatial Working Memory (SWM)	8 minutes	A measure of the key aspects of working memory and storage of information over short periods of time.
Beck Depression Inventory Scale of Measurement	5 minutes	Assessment of symptoms of depression pre and post-intervention cycle exercise. The Beck Depression Inventory is a 21-item, multiple-choice, self-report survey that measures characteristic attitudes and symptoms of depression. The score range is 0-63. The higher the score the more severe the depression. Scores above 41 are considered "extreme depression."
Neuropsychological Outcomes: Motor Screen Tasks (MOT)	3 minutes	MOT provides a general indication that psychomotor function is intact enough to proceed with more sophisticated cognitive testing:

Secondary Outcome Measures

Name	Time	Method
Neuropsychological Outcomes: MOT Mean Latency, MOT Total Correct, and MOT Total Errors	10 minutes	This test is a general assessment of whether there are sensorimotor deficits or lack of comprehension. Outcome is measured by reaction time in milliseconds of the participant reaching out and touching the "X" correctly (in the middle of the X) on the tablet in response to the stimulus. The maximum score is 6000 milliseconds. The number of total correct touches and total errors in not touching correctly out of 10 are recorded. Ex: MOT mean latency = 927.9 ml +/- 131.43 ms; MOT Total Correct = 10; MOT Total Errors = 0.

Trial Locations

Locations (1)

UTArlington; 🇺🇸 Arlington, Texas, United States