NL-OMON36248
Completed
Not Applicable
The effect of maltitol and xylitol sweetened chewing gum on caries risk factors of dental plaque and saliva, and on the development of gingivitis in a 21 day non-brushing study model - Maltitol and oral health
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- mondgezondheid
- Sponsor
- Roquette Freres
- Enrollment
- 220
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Male and female between18 and 30 years
- •\- Self classified as healthy
- •\- At least 5 evaluable teeth in each quadrant
- •\- With moderate gingivitis (30\-60% bleeding on marginal probing)
- •\- Non\-smokers
Exclusion Criteria
- •\- Any known allergy to any of the ingredients (xylitol or maltitol) of the study products
- •\- Current periodontitis with periodontal pocketing over 5mm
- •\- Any pathological change of the oral mucosa
- •\- Wearing of an (intra\-)oral piercing
- •\- Use of antibiotics in 30 days prior to the experiment
- •\- Participation in professional dental cleaning during the study period
- •\- Abuse of drugs, alcohol, etc.
- •\- Systemic disease such as diabetes or HIV
- •\- Pregnancy or breastfeeding
- •\- Participation in a clinical study within the previous 30 days
Outcomes
Primary Outcomes
Not specified
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