NL-OMON38887
Completed
Phase 4
The effect of maltitol sweetened chewing gum on the oral microbiology. - Effect of maltitol sweetened chewing gum on the oral microbiology.
ACTA Dental Research B.V. (ADR)0 sites150 target enrollmentTBD
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Microbiologie van de supragingivale tandplaque
- Sponsor
- ACTA Dental Research B.V. (ADR)
- Enrollment
- 150
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Male and female \- Age \*18 years \- Classified as systemically healthy, assessed by medical questionnaire \- Non\-smokers \- Minimum of 20 natural teeth: at least 5 evaluable teeth in each quadrant \- DPSI 0\-3\- \- With moderate gingivitis (30\-60% BOMP) \- No partial dentures \- No orthodontic banding \- No oral lesions \- Subjects who do not use a interdental device at home. \- No use of antibiotics 60 days before baseline \- No pregnancy/breast feeding \- No participation in clinical trials 30 days before baseline \- No consumer of \> 3 sugar free chewing gums a day \- Willing and able to give written informed consent \- No medication except for birth control pills
Exclusion Criteria
- •\- Anyone presenting with a probing depth \* 5mm with bleeding on probing and attachment loss \* 2 mm \- Overt dental caries \- Usage of any interdental device as part of regular daily oral care \- Smokers \- DPSI 3\+\-4 \- Removable (partial) dentures \- Crowns, bridges and implant supported restorations \- Removable night guard \- Oral and/or peri\-oral piercings \- Apparent oral lesions (aphthous ulcers excluded) \- Presence of orthodontic banding (except for lingual retention wire) \- Dental student or dental professional \- Participation in a clinical study within the previous 30 days ;General health and use of medication:
- •\- Self\-reported pregnancy or breastfeeding \- Use of antibiotics during the last 2 months \- Need of antibiotic prophylaxis prior to dental treatment \- Use of anti\-inflammatory drugs on a regular basis \- Evidence of any systemic disease or compromised health condition \- Adverse medical history or long\-term medication \- Prescribed medication (except for birthcontrol pills)
Outcomes
Primary Outcomes
Not specified
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