Detecting Absence Seizures Using Eye Tracking
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 150
- 试验地点
- 5
- 主要终点
- Eysz algorithm to detect absence seizures
研究概览
简要总结
The goal of this study is to develop a comfortable system that uses a wearable eye-tracker similar to eyeglasses to assist people with epilepsy in counting and measuring the severity of seizures. Participants will wear an eye-tracker during a routine EEG.
详细描述
Seizures can be difficult to detect outside of the hospital even with careful observation by a caregiver. EEG is the best method that we have to detect seizures- but it is uncomfortable for long term use outside of the hospital. The goal of this study is to develop a comfortable system that uses a wearable eye-tracker similar to eyeglasses to assist people with epilepsy in counting and measuring the severity of seizures. People participating in this study will have a routine EEG performed while an eye tracker measures eye movements. After the EEG is complete the researchers will compare the eye movements to the EEG to develop a software program that can detect seizures from eye movements.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 4 Years 至 100 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Provision of signed and dated informed consent form- per local IRB
- •Stated willingness to comply with all study procedures including the clicker test and availability for the duration of the study
- •Male or female, aged 4-100
- •Experience known typical absence seizures as defined by the ILAE 2017 classification or referred to EEG lab for staring spell or concern for absence seizure
- •a. This will allow for inclusion of children and adults across the entire spectrum of disease states including new diagnosis (medication naive), medication responsive and non-medication responsive
- •Scheduled for clinical EEG observation
排除标准
- •Intolerant of wearing or unable to wear the eyeglasses
- •Autism or other developmental disorder that the PI thinks will interfere with data collection
- •History of aggression that the PI thinks will interfere with data collection
- •History of not tolerating EEG that the PI thinks will interfere with data collection
- •Unable to give consent (for individuals ≥ 18 years old) unless they have an adult with power of attorney to consent
结局指标
主要结局
Eysz algorithm to detect absence seizures
时间窗: 1 hour
EEG is burdensome and limited. The current accepted method of counting seizures is observation which fails to identify \> 50% of seizures. The goal is to validate the Eysz absence seizure detection algorithm and show significant improvement over current standard of care
次要结局
未报告次要终点
研究者
Rachel Kuperman
Director, Clinical Research
Eysz, Inc.