The role of peri-operative gabapentin in the management of pain following tonsillectomy

Phase 3

• Conditions: Pain following tonsillectomy; Post-tonsillectomy analgesic consumption; Post-tonsillectomy nausea; Post-tonsillectomy vomiting; Post-tonsillectomy return to normal activity; Post-tonsillectomy return to normal diet; Surgery - Other surgery; Anaesthesiology - Pain management

• Registration Number: ACTRN12613000663752
• Lead Sponsor: Department of Surgical Sciences, University of Otago

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-06-19
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Participants will be aged 16 years and over, scheduled for elective tonsillectomy between January 2014 and December 2014

Exclusion Criteria

Exclusion criteria will include contraindications to gabapentin, other concurrent procedures, revision or unilateral tonsillectomy, inability to complete the scoring charts, and those with suspected malignancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome measure is post-operative pain.[This will be assessed using a VAS, scoring at 2, 4, and 6 hours following surgery and on post-operative days 1 to 14.]

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes will be post-operative analgesic consumption.[This will be assessed on post-operative days 1 to 14 by way of a questionnaire and recovery of un-used analgesia at the end of the 2 week period.];Post-operative nausea[Days 1-14 assessed by validated Postoperative Nausea and Vomiting (PONV) Intensity Scale.];Post-operative vomiting[Days 1-14 assessed by validated Postoperative Nausea and Vomiting (PONV) Intensity Scale.];Post-operative return to normal activity.[Indication by non-validated questionnaire developed specifically for this study of day return to normal activity (From days 1-14).];Post-operative return to normal diet.[Indication by non-validated questionnaire developed specifically for this study of day return to normal diet (From days 1-14).]