NL-OMON21346
Completed
Not Applicable
Multi-center, randomized clinical trial to study the impact of in-hospital guidance for acutely decompensated heart failure treatment by predefined NT-proBNP targets (>30% reduction in NT-proBNP during admission) on the reduction of readmission and mortality rates:NT-proBNP guided therapy versus conventional therapy for acutely decompensated heart failure.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acutely decompensated heart failureAcute heart failureAcuut hartfalenAcuut gedecompenseerd hartfalen
- Sponsor
- Academical Medical Center - University of Amsterdam
- Enrollment
- 400
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
/A
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Hospital admission because of clinically validated acutely decompensated heart failure. A clinical diagnosis of HF is made on the basis of a HF\-score of 2 points or higher;
- •2\.Elevated NT\-proBNP levels ≥1700 ng/L (≥200 pmol/L) on hospital admission;
Exclusion Criteria
- •1\. Severe Chronic Obstructive Pulmonary Disease (COPD) with FEV\<1l/min;
- •2\. Pulmonary embolism within 1 month prior to admission and pulmonary hypertension not caused by left ventricle dysfunction (LVD);
Outcomes
Primary Outcomes
Not specified
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