Can an antibacterial coating on surfaces in an intensive care unit (ICU) prevent methicillin-resistant Staphylococcus aureus (MRSA) acquisition in patients?

Not Applicable

Completed

• Conditions: Methicillin-resistant Staphylococcus aureus (MRSA) infection; Infections and Infestations

• Registration Number: ISRCTN31972004
• Lead Sponsor: Bundang Jesaeng Hospital

Brief Summary

2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/30509196 results

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-12-31
• Study Start: 2018-11-19
• Last Update Posted: 9 January 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 621

Inclusion Criteria

1. Admitted to the medical intensive care unit during the study period.

Exclusion Criteria

1. Aged <18 years
2. Hospitalized <72 hours

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MRSA acquisition assessed using culture results which were obtained from patients’ nares up to 48 hours after ICU admission and on discharge from ICU.

Secondary Outcome Measures

Name	Time	Method
<br> 1. Vancomycin-resistant Enterococcus spp. (VRE) acquisition assessed by reviewing culture results and medical records from admission until discharge from ICU<br> 2. Multidrug-resistant Acinetobacter baumannii (MRAB) acquisition assessed by reviewing culture results and medical records from admission until discharge from ICU<br> 3. Clostridium-difficile–associated disease (CDAD) acquisition assessed by reviewing culture results and medical records from admission until discharge from ICU<br> 4. Hospital-acquired infections (HAI), including bloodstream infection, pneumonia, and urinary tract infection as defined by The Centers for Disease Control and Prevention, assessed by reviewing culture results and medical records from admission until discharge from ICU<br>