The relationship between anti-Xa activity and the renal function in elderly patients who are on apixaba
- Conditions
- atrial fibrillation
- Registration Number
- JPRN-UMIN000020692
- Lead Sponsor
- Keio University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Not provided
Patients contraindicated for apixaban (1)Patients with a history of a hypersensitivity to the ingredients of apixaban (2)Patients with bleeding symptoms which can be of a clinical concern within 6 months (e.g., active gastric ulcers, platelets < 100000, hemoglobin < 10 g/dL, and s stroke within 10 days) (3)Patients with blood clotting defects and liver disease with a clinically important bleeding risk (4)Patients with renal failure (creatinine clearance < 15 mL/min) Severe liver dysfunction (AST and ALT of > 2-fold the upper limits of normal (ULN) and a total bilirubin of > 1.5-fold the ULN) Patients with valvular disorders requiring surgery Patients who cannot orally take drugs or visit the Outpatient Unit on a regular basis Patients with a prognosis of < one year Patients anticoagulated with heparin or enoxaparin
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method