Importance of special blood test in obese patients receiving blood thinner enoxaparin, posted for laparoscopic bariatric surgery
Not Applicable
- Conditions
- Health Condition 1: null- Morbidly obese patients(BMI more than 40Kg/m2 or BMI more than 35Kg/M2 with an obesity related co-morbidty), posted for laparoscopic bariatric surgery
- Registration Number
- CTRI/2017/08/009476
- Lead Sponsor
- arani KK
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Patients with morbid obesity (BMI more than 40 Kg/m2 or BMI more than 35 Kg/m2 with an obesity related co-morbidity), undergoing laparoscopic bariatric surgery
Exclusion Criteria
1. Patients on anticoagulants or antiplatelet drugs
2. Patients with h/o DVT and PE
3. Chronic liver disease (serum bilirubin above 2mg/dl)
4. Chronic renal disease (Cr Cl less than 30ml/min)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Anti-Xa levels - 2.7 ml of blood collected in Vacutainers (BD Franklin Lakes, NJ, USA), containing Buff. Na citrate, 0.109 M, 3.2%,to monitor anti-Xa levels <br/ ><br>Timepoint: Anti-Xa levels <br/ ><br>1. On the day of surgery, before starting operation at 8 AM (12 hrs after 1st dose of enoxaparin) <br/ ><br>2. 4 hrs after after the dose of enoxaparin, administered 8 hrs after surgery <br/ ><br>3. 2nd postoperative day, 4 hrs after the dose of enoxaparin <br/ ><br>4. 8th postoperative day, 4 hrs after the dose of enoxaparin <br/ ><br>5.15th postoperative day, 4 hrs after the dose of enoxaparin <br/ ><br>6. 30th postoperative day, 4 hrs after the dose of enoxaparin <br/ ><br>
- Secondary Outcome Measures
Name Time Method ltrasound clour Doppler mapping of leg veins to rule out presence of any asymptomatic DVTTimepoint: Preoperatve, on 8th and 30th postoperative days