Investigation of the Prognostic Value of pVO2 in Recipients of Left Ventricular Assist Devices
试验速览
- 阶段
- 不适用
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Outcome after implantation
研究概览
简要总结
Pooling of earlier VO2-studies conducted at the dept. of cardiology, Rigshospitalet, Denmark, and all LVAD centres of the World that wish to participate.
The purpose is to investigate the prognostic value of VO2 in recipients of durable LVADs using data from studies already conducted.
详细描述
Background and purpose:
Peak oxygen uptake (pVO2) is used extensively in HF to predict prognosis and time for heart transplantation. Many centers are increasingly measuring pVO2 in LVAD supported HF patients, though this has mostly been for research or rehabilitation purposes. It is unknown if pVO2 predicts outcome in LVAD treated HF patients.
The investigators will pool data from all willing centers of the World to investigate the prognostic value of pVO2 (e.g. outcome in LVAD supported patients) and, secondly the investigators will investigate wether the predictive power of pVO2 in LVAD recipients depends on the treatment indication (BTT and DT).
Methods:
Data is collected in anonymized form from all centers willing to contribute data.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Durable LVAD implantation
- •VO2 in stable post implant phase
排除标准
- •No VO2 data available
- •Concomittant RVAD (temp/durable device)
结局指标
主要结局
Outcome after implantation
时间窗: Stable-phase post implant VO2 (e.g. >3months and up to 13 year post implant)
Survival/ongiong on device/explant/htx after LVAD implantation
次要结局
未报告次要终点
研究者
Finn Gustafsson
Professor
Rigshospitalet, Denmark