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Clinical Trials/NCT06359743
NCT06359743
Active, not recruiting
Not Applicable

Ultrasound Guided Quadratus Lumborum Block Versus Laparoscopic Superior Hypogastric Plexus Block for Postoperative Analgesia After Laparoscopic Hysterectomy

Zagazig University1 site in 1 country34 target enrollmentApril 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Post Hysterectomy Pain
Sponsor
Zagazig University
Enrollment
34
Locations
1
Primary Endpoint
Opioid consumption decrease
Status
Active, not recruiting
Last Updated
2 years ago

Overview

Brief Summary

Pain following laparoscopic hysterectomy may interfere with early ambulation, discharge of patient from hospital and interfere with enhanced recovery with more opioid consumption. Most of methods for postoperative pain depend on the use of high doses of opioids with more side effects such as nausea, vomiting, respiratory center depression, delay bowel motility and hemodynamics instability. To decrease of opioid consumption in postoperative pain management as well as related side effects, previous studies showed that quadratus lumborum block or superior hypogastric plexus block (SHPB) had shown promising success in management of postoperative pain in patients undergoing laparoscopic hysterectomy. The present study will be conducted to compare of ultrasound guided QL block and laparoscopic superior hypogastric plexus block as a part of multimodal analgesia may allow adequate analgesia and decrease the overall use of opioids and allow patient enhanced recovery.

Detailed Description

hypothesis: There is no difference between the analgesic effect of either Ultrasound guided QL block or laparoscopic Superior hypogastric plexus block on post laparoscopic hysterectomy pain. Alternative hypothesis: There is difference between the analgesic effect of either Ultrasound QL block or laparoscopic superior hypogastric plexus block on post laparoscopic hysterectomy pain. Aim of the work Better achievement of effective analgesia with less opioid consumption and related side effects for post laparoscopic hysterectomy pain. Objectives To assess effect of both ultrasound quadratus lumborum block and laparoscopic superior hypogastric plexus block on analgesic outcome (Visual Analogue Scale VAS, duration of analgesia) after laparoscopic hysterectomy. To compare between ultrasound quadratus lumborum block and laparoscopic superior hypogastric plexus block regarding to total opioid for postoperative analgesia after laparoscopic hysterectomy and patient satisfaction. To record side effects related to regional block ( e.g., local anesthetic toxicity, vascular and neural injury) and opioids ( neasuea, vomiting, respiratory depression

Registry
clinicaltrials.gov
Start Date
April 1, 2024
End Date
September 1, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Abdalla Mohamed Goda Mohamed

Abdalla mohamed goda mohamed ,MD

Zagazig University

Eligibility Criteria

Inclusion Criteria

  • Written informed consent from the patient.
  • BMI of less than or equal 30.0 kg m-
  • Age 45-60 years old.
  • American Society of Anesthesiologists (ASA) physical status classes I and II.

Exclusion Criteria

  • Allergy to local anesthetics.
  • Infection at site of injection.
  • Patients with coagulopathy.
  • Patients with chronic pain syndromes.
  • Physical and mental disease which could interfere with pain scores evaluation.
  • Patients with distorted local anatomy.

Outcomes

Primary Outcomes

Opioid consumption decrease

Time Frame: 24hours

Avoid excessive usage of opioid by regional blocks

Study Sites (1)

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