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COVID-19 Vaccine Hesitancy Among Rheumatic Diseases Patients

Completed
Conditions
Covid19
Interventions
Other: COVID-19 vaccine hesitancy scale in rheumatic diseases
Other: COVID-19 vaccine hesitancy associated factors
Registration Number
NCT04775563
Lead Sponsor
National Institute of Medical Sciences and Nutrition, Salvador Zubiran
Brief Summary

Rheumatological diseases (RD) are an important group of different clinical entities and specific diseases that affect a significant proportion of the world population. In Mexico, the RD have a relevant representation in the adult population. COVID-19 vaccination has been proposed as a measure to contain the COVID-19 pandemic. The vaccines have been shown to be effective and reasonably safe in the population without significant risk factors, which has allowed their approval to attend the health emergency. At present, there is little scientific information that allows a solid recommendation on vaccination for COVID-19 in patients with RD, although most authorities have spoken in favor of vaccination in immunocompromised patients, as are a relevant number of patients with RD. However, it is desirable to achieve herd immunity to facilitate the impact of vaccination on the transmission of SARS-CoV-2 infection. For this, it is required that around 70% -80% of the target population be vaccinated, which implies not only access to the vaccine but also accepting to be vaccinated.

Vaccine hesitancy is defined as the delay or refusal to accept the vaccine when it is available by health services. Sometimes, they conceptualize it as a continuum and also includes the high demand from the population for the vaccine; In this continuum, there are variations in acceptance and rejection and multiple possible combinations, from acceptance with great concern about the decision to rejection of certain vaccines but not others. It is a complex, contextual, changing phenomenon, specific for each vaccine and the referred disease and probably influenced by cultural determinants.

Detailed Description

The objectives are:

1. - To measure the phenomenon of vaccine hesitancy in Mexican patients with RD from two Health Institutions in Mexico City.

2. - Translate and adapt the "Oxford Covid-19 vaccine hesitancy scale" to patients with RD and validate this version in a population of patients with RD from two Health Institutions in Mexico City

3. Explore factors associated with the phenomenon of vaccine hesitancy.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
891
Inclusion Criteria
  • Patients with a rheumatic disease diagnosis according to their primary rheumatologist who agree to participate
Exclusion Criteria
  • Patients with a not confirmed rheumatic disease

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Rheumatic diseases outpatientsCOVID-19 vaccine hesitancy scale in rheumatic diseasesAll the rheumatic diseases outpatients from the National Institute of Medical Sciences and General Hospital.
Rheumatic diseases outpatientsCOVID-19 vaccine hesitancy associated factorsAll the rheumatic diseases outpatients from the National Institute of Medical Sciences and General Hospital.
Primary Outcome Measures
NameTimeMethod
Measure the phenomenon of vaccine hesitancy among rheumatic diseases patientsAt study inclusion

Identify the percentage of patients with rheumatic diseases that present COVID-19 vaccine hesitancy using the instrument developed by Freeman et al (translation, cultural adaptation, and validation performed)

Secondary Outcome Measures
NameTimeMethod
Identify factors associated with COVID-19 vaccine hesitancy among rheumatic diseases patientsAt study inclusion

Identify factors associated with COVID-19 vaccine hesitancy among rheumatic diseases patients using an instrument locally development

Trial Locations

Locations (1)

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

🇲🇽

Mexico City, Mexico

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