How effective is Physical Therapy for gait muscle activity in hemiparetic patients who received botulinum toxin injections?

Not Applicable

• Conditions: Stroke

• Registration Number: JPRN-UMIN000030102
• Lead Sponsor: Fukui Health Science University

Brief Summary

In this study, marked changes in muscle activity occurred in patients with stroke who had physical therapy after BoNT-A administration to the ankle plantar flexor muscles. These changes were increased biceps femoris activity and increased co-activation indices for the rectus femoris and biceps femoris during the loading-response phase, and increased tibialis anterior activity and decreased triceps surae and rectus femoris activities in the pre-swing and swing phases. Almost all patients in both treatment groups showed improved walking speed, and none reported gait deterioration. Physical therapy after BoNT-A administration increased the stability and leg-swing capability of the knee and could prevent decreased walking ability.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-11-24
• Study Completion: 2018-08-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

Not provided

Exclusion Criteria

1. Higher brain dysfunction that presents problems for intervention and/or evaluation; 2. Cardiovascular disease that restricts exercise; 3. BoNT-A administration within the previous 4 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Gait electromyography was performed and gait parameters were measured immediately before and 2 weeks after BoNT-A administration.