Early Detection of Disability and Health Promotion for Community-dwelling Elderly

Not Applicable

• Conditions: Elderly; Sarcopenia
• Interventions: Other: exercise training

• Registration Number: NCT03607136
• Lead Sponsor: Buddhist Tzu Chi General Hospital

Brief Summary

This study evaluates the effects of exercise intervention on muscle strength and walking speed for the community-dwelling elderly. Half of the participants will receive exercise training, while the other half will maintain their usual activities of daily living.

Detailed Description

Physical inactivity can result in physical frailty and sarcopenia. Physical frailty and sarcopenia are two common and mostly overlapping geriatric conditions, which may cause negative consequences of aging, such as disability, hospitalization and mortality.

Regular physical activity has been suggested to maintain or improve functional capacity and body composition, as well as delay aging process. Nevertheless, inactivity prevalence still significantly increases among older adults, especially those with a disability. One of the probable reasons is that the use of physical activities or exercise interventions is not tailored to the needs and capabilities of the elderly.

Study Timeline

• Status Verified: 2018-07
• Study First Submitted: 2018-07-05
• Study First Submitted QC: 2018-07-23
• Last Update Submitted: 2018-07-23
• Study First Posted: 2018-07-31
• Last Update Posted: 2018-07-31
• Study Start: 2018-08
• Primary Completion: 2019-07
• Study Completion: 2020-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• age greater than 50 years
• able to follow simple instructions
• willing to participate and sign consent form

Exclusion Criteria

• unstable angina or epilepsy
• severe visual deficits
• cognitive dysfunction
• other musculoskeletal conditions that will limit mobility

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
exercise training	exercise training	Participants in the exercise training group received a 12-week exercise training.

Primary Outcome Measures

Name	Time	Method
Walking speed	Change from baseline at 12 weeks	Participants are asked to walk along a 14 m hallway. The time taken to the middle 10 m is recorded to calculate walking speed (m/s).
Muscle strength	Change from baseline at 12 weeks	Muscle strength is assessed using hand-hold Dynamometers

Secondary Outcome Measures

Name	Time	Method
Walking endurance	Change from baseline at 12 weeks	Participants are asked to walk back and forth along a 20-meter corridor and to cover the maximum distance possible in six minutes
Sit-to-stand test	Change from baseline at 12 weeks	Participants are asked to stand up and sit down 5 times.
Timed up and go test	Change from baseline at 12 weeks	Participants are asked to stand up, walk 3 m, turn around a cone, and return to a sitting position
Berg balance scale	Change from baseline at 12 weeks	It consists of 14 items, including sitting unsupported, standing unsupported, standing with eyes closed, standing with feet together, standing on one foot, turning to look behind, retrieving objective from floor, random standing, reaching forward with an outsrptretched arm, sit to stand, stand to sit, transfer, turning 360 degrees, stool stepping, scored from 0 to 4, "0" indicates the lowest level of function and "4" the highest level of function. Total Score = 56.
Gait kinematics	Change from baseline at 12 weeks	Gait kinematics are assessed by angular displacement of lower limbs using shoe-worn inertial measurement unit based device