Study of the Clinical Presentations, Treatment and Outcomes of Infective Endocarditis Patients in a Tertiary Hospital in East China
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Infective Endocarditis
- Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Enrollment
- 183
- Primary Endpoint
- Complications (neurological events, systemic embolism, and congestive heart failure) of infective endocarditis
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
This was a retrospective observational study of consecutive cases of definite or possible infective endocarditis (IE) as per the modified Duke criteria between January 2008 and December 2015, which was performed at the Second Affiliated Hospital of Zhejiang University, School of medicine (SAHZU), a tertiary care referral hospital located in East China.
Detailed Description
Infective endocarditis (IE) is a rare but life-threatening serious disease that still has a high mortality, even in developed countries. The objective of this study was to evaluate the clinical presentations, treatment and outcomes of IE patients in a tertiary hospital in East China over an 8-year period. This was a retrospective observational study of consecutive cases of definite or possible IE as per the modified Duke criteria between January 2008 and December 2015.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with a clinical diagnosis of infective endocarditis.
Exclusion Criteria
- •Patients did not meet the modified Duke criteria.
Outcomes
Primary Outcomes
Complications (neurological events, systemic embolism, and congestive heart failure) of infective endocarditis
Time Frame: During the hospitalization, average of 1 months
1. A neurological event was defined as symptomatic or asymptomatic stroke, hemorrhage, or encephalopathy. 2. Systemic embolization was defined as an embolic event outside of the central nervous system. 3. Congestive heart failure was defined as with class III, or IV heart failure and an ejection fraction of 40% or less.
Mortality
Time Frame: During the hospitalization, average of 1 months
Patients dead or moribund before discharge