Bone Geometry, Volumetric Density, Microarchitecture and Estimated Bone Strength Assessed by High Resolution Peripheral Quantitative Computed Tomography in Patients with Adult Onset Growth Hormone Deficiency

Odense University Hospital3 sites in 1 country45 target enrollmentSeptember 2014

ConditionsAdult Onset Growth Hormone Deficiency

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Adult Onset Growth Hormone Deficiency
Sponsor: Odense University Hospital
Enrollment: 45
Locations: 3
Primary Endpoint: volumetric bone mineral density in grams per cc
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of the study is to assess bone geometry, bone compartment specific volumetric densities and micro-architecture as well as to evaluate non-invasive estimates of bone strength in patients with adult onset growth hormone deficiency.

Registry

clinicaltrials.gov

Start Date

September 2014

End Date

June 2019

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

Odense University Hospital

Responsible Party

Principal Investigator

Marianne Andersen

Associate Professor, DM, DMSc, PhD

Odense University Hospital

Eligibility Criteria

Inclusion Criteria

•Men and women diagnosed with Adult onset Growth Hormone Deficiency
•Age between 18-80
•Informed consent

Exclusion Criteria

•Competing bone disease (e.g.. Mb. Paget, myelomatosis, osteogenesis imperfecta, osteoporosis, primary hyperparathyroidism)
•Ongoing medical treatment affecting bone metabolism (eg. osteoporosis medications)
•Ongoing pregnancy or breast feeding