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Bone Structure in Patients With Adult Onset Growth Hormone Deficiency Assessed Using High Resolution Peripheral Quantitative Computed Tomography

Conditions
Adult Onset Growth Hormone Deficiency
Registration Number
NCT02218710
Lead Sponsor
Odense University Hospital
Brief Summary

The aim of the study is to assess bone geometry, bone compartment specific volumetric densities and micro-architecture as well as to evaluate non-invasive estimates of bone strength in patients with adult onset growth hormone deficiency.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
45
Inclusion Criteria
  • Men and women diagnosed with Adult onset Growth Hormone Deficiency
  • Age between 18-80
  • Informed consent
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Exclusion Criteria
  • Competing bone disease (e.g.. Mb. Paget, myelomatosis, osteogenesis imperfecta, osteoporosis, primary hyperparathyroidism)
  • Ongoing medical treatment affecting bone metabolism (eg. osteoporosis medications)
  • Ongoing pregnancy or breast feeding
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
volumetric bone mineral density in grams per cc1 year
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Endocrinological department M, Odense University Hospital

🇩🇰

Odense, Region syddanmark, Denmark

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