Role of Hematological Parameters in the Stratification of COVID-19 Disease Severity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 101
- 试验地点
- 1
- 主要终点
- complete blood count- Hemoglobin. White blood count, platelet count, Neutrophil to lymphocyte ratio
研究概览
简要总结
The hemostatic abnormalities in COVID-19 are related with disease progression, severity and mortality. The Objective of our study is to evaluate the role of hematological parameters in determination of COVID-19 disease severity.
详细描述
Objective
COVID-19 virus involves respiratory as well as other body systems including cardiovascular, gastrointestinal, neurological, immunological and hematopoietic system. Patient of covid-19 pneumonia presents with wide range of hemostatic abnormalities. These hemostatic abnormalities in COVID-19 are related with disease progression, severity and mortality. The Objective of our study is to evaluate the role of hematological parameters in determination of COVID-19 disease severity.
Material and Method:
This was a retrospective study, conducted in Department of Pathology and Department of medicine, FMH college of Medicine and Dentistry from May 2020 to July 2020. Total of 101, confirmed cases of covid-19 disease, both genders between 17 to 75-year age were included. Hematological parameters were compared in mild, moderate, severe and critical disease group. Continuous variables were analyzed by using non parametric, Kruskal Wallis test while categorical variables were analyzed by chi-square test.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 17 Years 至 75 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosed cases of covid-19 disease
- •Both genders
- •17 to 75 year age
排除标准
- •known case of chronic liver disease
- •known hematological diseases were excluded
结局指标
主要结局
complete blood count- Hemoglobin. White blood count, platelet count, Neutrophil to lymphocyte ratio
时间窗: 3 months
disease severity was assessed on basis of hematological parameters.
次要结局
- PT, APTT and D-dimer(3 months)
研究者
Sadia Taj
Assistant Professor
FMH College of Medicine and Dentistry