Role of Hematological Parameters in the Stratification of COVID-19 Disease Severity
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Covid19
- Sponsor
- FMH College of Medicine and Dentistry
- Enrollment
- 101
- Locations
- 1
- Primary Endpoint
- complete blood count- Hemoglobin. White blood count, platelet count, Neutrophil to lymphocyte ratio
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The hemostatic abnormalities in COVID-19 are related with disease progression, severity and mortality. The Objective of our study is to evaluate the role of hematological parameters in determination of COVID-19 disease severity.
Detailed Description
Objective: COVID-19 virus involves respiratory as well as other body systems including cardiovascular, gastrointestinal, neurological, immunological and hematopoietic system. Patient of covid-19 pneumonia presents with wide range of hemostatic abnormalities. These hemostatic abnormalities in COVID-19 are related with disease progression, severity and mortality. The Objective of our study is to evaluate the role of hematological parameters in determination of COVID-19 disease severity. Material and Method: This was a retrospective study, conducted in Department of Pathology and Department of medicine, FMH college of Medicine and Dentistry from May 2020 to July 2020. Total of 101, confirmed cases of covid-19 disease, both genders between 17 to 75-year age were included. Hematological parameters were compared in mild, moderate, severe and critical disease group. Continuous variables were analyzed by using non parametric, Kruskal Wallis test while categorical variables were analyzed by chi-square test.
Investigators
Sadia Taj
Assistant Professor
FMH College of Medicine and Dentistry
Eligibility Criteria
Inclusion Criteria
- •diagnosed cases of covid-19 disease
- •Both genders
- •17 to 75 year age
Exclusion Criteria
- •known case of chronic liver disease
- •known hematological diseases were excluded
Outcomes
Primary Outcomes
complete blood count- Hemoglobin. White blood count, platelet count, Neutrophil to lymphocyte ratio
Time Frame: 3 months
disease severity was assessed on basis of hematological parameters.
Secondary Outcomes
- PT, APTT and D-dimer(3 months)