Clinical correlation between breast cancer and prognostic significance of ferritin,vitamin D and vitamin B12.
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Akansha Hatewar
- Enrollment
- 42
- Locations
- 1
- Primary Endpoint
- 1 To estimate levels of serum vit D, Vit B12, and Ferritin in patients with stages of breast cancer.
Overview
Brief Summary
In this study, we aim to conduct a comprehensive analysis by comparing serum expression levels of vitamin B12, vitamin D, and ferritin among three distinct groups: healthy individuals, patients with benign breast conditions, and those diagnosed with breast cancer. Our primary focus is to assess the intricate relationship between vitamin B12, vitamin D, and ferritin levels and the associated risk of breast cancer. By examining these parameters across various health conditions, we intend to gain a deeper understanding of how these vitamins may play a pivotal role in breast cancer risk. This research holds the potential to shed valuable light on the connections between these serum markers and the development of breast cancer, ultimately contributing to our knowledge of this complex disease.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 95.00 Year(s) (—)
- Sex
- Female
Inclusion Criteria
- •1 Newly diagnosed case of CA breast and biopsy proven.
- •2 Women aged above 18 years.
Exclusion Criteria
- •1 Malignancies other than breast carcinoma 2 Pregnancy/puerperium 3 Known c/o Tuberculosis, Chronic inflammatory diseases 4 Patients infected with hepatitis B and C virus as well as H.I.V. 5 Renal/Hepatic insufficiency 6 Metabolic bone disorders 7 No history of medications such as iron, levothyroxine and vitamin D/B12 supplements in the past three months.
Outcomes
Primary Outcomes
1 To estimate levels of serum vit D, Vit B12, and Ferritin in patients with stages of breast cancer.
Time Frame: 2 years
2 To analyse a correlation between serum vit D, Vit B12, Ferritin with Tumour grade, histopathological subtype and axillary lymph node status.
Time Frame: 2 years
3 To correlate between serum vit D, Vit B12, and Ferritin with molecular pathological parameters.
Time Frame: 2 years
Secondary Outcomes
- 1. In this study we aim to conduct a comprehensive analysis by comparing serum expression levels of vitamin B12 vitamin D & ferritin among three distinct groups healthy individuals patients with benign breast conditions & those diagnosed with breast cancer.(2. Our primary focus is to assess the intricate relationship between vitamin B12 vitamin D & ferritin levels & the associated risk of breast cancer.)
Investigators
Dr Akansha Hatewar
Datta Meghe Institute Of Higher Education And Research