NL-OMON46823招募中不适用
Epilepsy surgery evaluation in patients with refractory epilepsy: prospective application of routine genetic testing - GENetics & Epilepsy Surgery 1 / GENES 1
eurologie0 个研究点目标入组 275 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 275
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 2 至 99(—)
入选标准
- •In order to be eligible to participate in this study, a subject must meet all of the following criteria:
- •o The patient enters the presurgical evaluation program in one of the participating centers
- •o No age limit
- •o Patients and/or parents/legal representative are willing and able to give informed consent for participation in the study.
- •o MRI-brain shows no abnormalities that are likely to be causative for the epilepsy (*MRI-negative*: As determined by the local neuroradiologist and MD team, independent of the used MR imaging protocol, field strength, or post-processing.);Cohort II
- •o The patient entered the presurgical evaluation program in in the UMC Utrecht
- •o No age limit
- •o Patients and/or parents/legal representative are willing and able to give informed consent for participation in the study
- •o The patient underwent surgery in the UMC Utrecht for drug-resistant FE and had MCD, GNT, or negative pathology
排除标准
- •A potential subject who meets any of the following criteria will be excluded from participation in this study:
- •o No age exclusion criteria
- •o Known genetic disorders at entry that are directly related to the patient*s epilepsy; genetic disorders not related to the epilepsy are not a reason for exclusion, however such conditions will be noted in the participant*s research file.
研究者
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