Comprehensive cognitive and physical function assessment and develpoed severity scoring model for patients with sarcopenia
- Conditions
- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- KCT0008867
- Lead Sponsor
- InBody
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Adult men and women over 50 years of age
-Able to walk independently
- Those who understand the explanation of this study and agree to participate
? People with neurological diseases that affect walking
(e.g., traumatic brain injury (TBI), stroke, multiple sclerosis)
? Those who have undergone orthopedic surgery within the last 6 months or have had a central fracture (central bone: spine, pelvis, lower extremity) within 1 year
? Liver level (more than 3 times the upper normal limit)
? Those with abnormalities in kidney function (eGFR <30ml/min or Cr >1.2)
? Chronic disease patients
(a) Type 1 diabetes or uncontrolled type 2 diabetes (fasting blood sugar = 160mg/dl),
(b) Uncontrolled hypertension (>160/100 mmHg),
(c) heart failure (NYHA class 3,4),
(d) chronic obstructive pulmonary disease (COPD, grade C, D),
(e) Those with liver cirrhosis (Child-Pugh B, C)
? Those who have been diagnosed with cancer requiring treatment within the last 5 years
? Those who are unable to measure grip strength and lower extremity strength
? Persons with cognitive decline to the point where they cannot follow instructions
? Any other person who is unable to participate in the study at the discretion of the PI (principal investigator)
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Skeletal Muscle Index (SMI)
- Secondary Outcome Measures
Name Time Method gait speed ;five times sit to stand test (FTST);Timed up and go (TUG);Low extremity muscle strength;MVC amplitude of Quadriceps muscle surface EMG ;Korean version of SARC-F ;Korean version of Patient Health Questionnaire-9(PHQ-9);Korean version of EuroQol-5 Dimension(EQ-5D-5L);Korean Version of Montreal Cognitive Assessment (MoCA-K);coding of Koren Wechsler Adult Intelligence Scale-4 evaluation items(K-WAIS-4; coding) ;Cogscreen, EmoCog® (Smartphone App embedded cognitive function assessent tool);hand grip strength;step length ;Double limb support time ;PDT, EmoCog® (Smartphone App. embedded neurodegenerative disease screening tool)