Understanding the Effects of Intervention on the Brain in Autism

Not Applicable

Active, not recruiting

• Conditions: Autism Spectrum Disorder; Autism; PDD-NOS; Asperger Disorder
• Interventions: Behavioral: PEERS

• Registration Number: NCT02680015
• Lead Sponsor: Marquette University

Brief Summary

This study examines how the PEERS (Laugeson \& Frankel, 2010; Laugeson, 2016) social-behavioral intervention affects social relationships and brain development and function in autistic preschoolers, adolescents, and young adults.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-08
• Study First Submitted: 2016-02-04
• Study First Submitted QC: 2016-02-08
• Study First Posted: 2016-02-11
• Status Verified: 2023-04
• Last Update Submitted: 2023-04-17
• Last Update Posted: 2023-04-19
• Primary Completion: 2023-05
• Study Completion: 2023-05

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• Verbal, speaking in full sentences
• Meets ASD criteria
• Meets IQ criteria >70

Exclusion Criteria

• schizophrenia or bipolar disorder

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Experimental Group	PEERS	Immediate enrollment in the PEERS group.

Primary Outcome Measures

Name	Time	Method
Test of Adolescent Social SKills (TASSK: Laugeson & Frankel, 2010)	within two weeks of PEERS completion	Questionnaire completed by participants with Autism Spectrum Disorder. Measures knowledge of the PEERS intervention concepts. Will be aggregated by group; no individual reports will be used.
Social Responsiveness Scale (SRS: Constantino, 2005)	within two weeks of PEERS completion	Questionnaire completed by caregivers on social function and autism symptoms. Will be aggregated by group; no individual reports will be used.

Trial Locations

Locations (1)

Marquette University; 🇺🇸 Milwaukee, Wisconsin, United States