The Effects of Vitamin D Supplementation in Respiratory Index of Severity in Children (RISC) of Hospitalized Patients With Community-acquired Pneumonia
Overview
- Phase
- Phase 4
- Intervention
- Placebo
- Conditions
- Pneumonia
- Sponsor
- Hormozgan University of Medical Sciences
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Respiratory Index of Severity in Children (RISC)
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
Childhood deaths from pneumonia is almost 2000 times higher in developing countries than in developed countries. In 1970, pneumonia was responsible for 9% of all deaths in children under 5 years. This rate was 2% in 2007.
Some studies have shown that supplementing with vitamin D reduces disease of the respiratory tract infection. Some other studies have shown anti-inflammatory effect of vitamin D in cell lines. Studies about the role of vitamin D supplementation in pneumonia in children are inadequate to conclude about its role.
The aim of this study is to determine the efficacy of vitamin D supplementation in Respiratory Index of Severity in Children (RISC) hospitalized clinical outcomes of hospitalized patients with community-acquired pneumonia.
Investigators
Hamidreza Mahboobi
Dr
Hormozgan University of Medical Sciences
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Arms & Interventions
Placebo
Placebo (same size and shape) for 2 days
Intervention: Placebo
Vitamin D3 (Low dose)
vitamin D at a dose of 50,000 IU per day for 2 days
Intervention: Vitamin D3
Outcomes
Primary Outcomes
Respiratory Index of Severity in Children (RISC)
Time Frame: through study completion, an average of 4 days
For determining severity of pneumonia, RISC (Respiratory Index of Severity in Children) scoring system was used, including oxygen saturation, chest retraction, wheezing and refusal to feed, and also contains standards growth (weight for age).
Secondary Outcomes
- Duration of hospitalization(through study completion, an average of 4 days)