The Effect of Carbohydrate Feeding Frequency on Muscle Glycogen and Exercise Capacity in Runners
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 7
- 试验地点
- 2
- 主要终点
- Muscle glycogen concentrations
研究概览
简要总结
The aim of this study is to investigate the effects of regular sucrose feeds compared to a single large bolus given late in exercise, on muscle glycogen utilisation, exercise capacity and other markers of metabolism during running
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Self-identify as a trained runner
- •Regularly participate in running activity (>2 times a week)
- •Participated in running based training for a minimum of 2 years
- •Be willing to undertake exercise sessions until volitional exhaustion
- •Be willing to have the necessary samples taken during the testing protocols
- •Not a habitual smoker
- •Have the capacity and willingness to provide informed consent (oral and written)
- •Successful completion of the physical activity readiness questionnaire (PAR-Q)
排除标准
- •<18 or >50 years old
- •Not regularly participating in running activity (<3 times a week)
- •Experience contraindications to the administration of the proposed anaesthetic (Lidocaine Hydrochloride)
- •Habitual/previously habitual smoker
研究组 & 干预措施
Regular carbohydrate feeding
Ingestion of 75 g sucrose, given in regular doses for the first 75 minutes of exercise during a time to exhaustion run
干预措施: Regular carbohydrate feeding (Other)
Single carbohydrate bolus
Ingestion of 75 g sucrose, given in a single bolus after 75 minutes of exercise, during a time to exhaustion run
干预措施: Single carbohydrate bolus (Other)
结局指标
主要结局
Muscle glycogen concentrations
时间窗: Estimated to be between 90 and 145 minutes
Muscle glycogen concentration at rest, after 75 minutes of treadmill running and at volitional exhaustion. Measured using the bergstrom needle technique for obtaining muscle biopsy samples
Exercise capacity
时间窗: Estimated to be between 90 and 145 minutes
Time to exhaustion at the pre-determined speed to elicit exhaustion after \~90 minutes when ingesting water only
次要结局
- Ratings of perceived exertion(Estimated to be between 90 and 145 minutes)
- Fat oxidation(Estimated to be between 90 and 145 minutes)
- Plasma lactate concentrations(Estimated to be between 90 and 145 minutes)
- Rate of oxygen consumption(Estimated to be between 90 and 145 minutes)
- Rate of carbon dioxide production(Estimated to be between 90 and 145 minutes)
- Ratings of stomach discomfort(Estimated to be between 90 and 145 minutes)
- Carbohydrate oxidation(Estimated to be between 90 and 145 minutes)
- Plasma glucose concentrations(Estimated to be between 90 and 145 minutes)
- Heart rate(Estimated to be between 90 and 145 minutes)
研究者
James Betts
Professor, Department for Health
University of Bath