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Clinical Trials/NCT00657436
NCT00657436
Completed
Not Applicable

Study of Myeloid-related Protein 8/14 and Additional Biomarkers (Multi Marker Approach) for Early Diagnosis and Risk Stratification in Patients Presenting With Acute Chest Pain at the Emergency Department

University of Zurich1 site in 1 country403 target enrollmentMarch 2008
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ConditionsMyocardial IschemiaAcute Coronary SyndromeMyocardial InfarctionCoronary OcclusionCoronary Thrombosis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Myocardial Ischemia
Sponsor
University of Zurich
Enrollment
403
Locations
1
Primary Endpoint
Diagnosis of acute coronary syndrome
Status
Completed
Last Updated
13 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of the study is the evaluation of multiple biomarkers related to acute coronary syndromes, including myeloid-related protein 8/14 (MRP 8/14), along with established clinical markers, for early diagnosis and risk stratification in patients presenting with acute chest pain at the emergency department.

Study hypothesis: MRP 8/14, alone or together with other established or new biomarkers, increases the earliness, sensitivity, and specificity of diagnosing acute coronary syndromes.

Registry
clinicaltrials.gov
Start Date
March 2008
End Date
December 2010
Last Updated
13 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •All patients in the emergency department of the University Hospital Zurich with measurement of troponin during the routine diagnostic evaluation.

Exclusion Criteria

  • •Refusal or inability to give informed consent.

Outcomes

Primary Outcomes

Diagnosis of acute coronary syndrome

Time Frame: Emergency room and/or hospital stay

Secondary Outcomes

  • Incidence of any acute coronary event(1 year)
  • Morbidity from coronary artery disease(1 year)
  • Mortality(1 year)

Study Sites (1)

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