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临床试验/NCT00657436
NCT00657436已完成不适用

Study of Myeloid-related Protein 8/14 and Additional Biomarkers (Multi Marker Approach) for Early Diagnosis and Risk Stratification in Patients Presenting With Acute Chest Pain at the Emergency Department

University of Zurich1 个研究点 分布在 1 个国家目标入组 403 人开始时间: 2008年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
403
试验地点
1
主要终点
Diagnosis of acute coronary syndrome

研究概览

简要总结

The purpose of the study is the evaluation of multiple biomarkers related to acute coronary syndromes, including myeloid-related protein 8/14 (MRP 8/14), along with established clinical markers, for early diagnosis and risk stratification in patients presenting with acute chest pain at the emergency department.

Study hypothesis: MRP 8/14, alone or together with other established or new biomarkers, increases the earliness, sensitivity, and specificity of diagnosing acute coronary syndromes.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients in the emergency department of the University Hospital Zurich with measurement of troponin during the routine diagnostic evaluation.

排除标准

  • Refusal or inability to give informed consent.

结局指标

主要结局

Diagnosis of acute coronary syndrome

时间窗: Emergency room and/or hospital stay

次要结局

  • Incidence of any acute coronary event(1 year)
  • Morbidity from coronary artery disease(1 year)
  • Mortality(1 year)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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